THE BEST SIDE OF LIMITED EDITION EXCLUSIVE LSD CRYSTAL)

In the LSD-bound crystal framework, the side chain with the lid residue L209EL2 varieties intensive hydrophobic contacts with both of those LSD and bordering residues in TMs III, IV, and V (Determine 4C). Once the lid moved apart to reveal the binding pocket in simulation, various of such contacts broke. We Therefore hypothesized that L209EL2 acts